Catheter-Directed Therapy vs Anticoagulation in Intermediate-Risk PE (HI-PEITHO):
Catheter-Directed Therapy vs Anticoagulation in Intermediate-Risk PE (HI-PEITHO):
Early Benefit… in Selected Patients (Follow-up: 7 days)
• ↓ Primary events 61%(No ↑ major bleeding. No mortality difference
Only in carefully selected patients)
Selection Basis:
• RV dysfunction (RV/LV ≥ 1.0)
• ↑ Troponin
• ≥2 signs of cardiorespiratory stress
Closest to Category D (pre-shock)
Source
• TCTMD — ACC 2026 Conference Coverage
• NEJM (simultaneous publication)
Link (direct):
https://www.tctmd.com/news/hi-
