Impella + PCI vs PCI Alone (STEMI-DTU): No Benefit… More Harm

• No reduction in infarct size
•  ↑ major bleeding & vascular complications (~6×)
• No improvement in clinical outcomes
• Population: Anterior STEMI without shock

 Routine use not recommended

Source
• TCTMD — ACC 2026 Conference Coverage
• JACC (simultaneous publication)

 Link (direct):
https://www.tctmd.com/news/mechanical-circulatory-support-doesnt-reduce-infarct-size-stemi