LDL <55 vs <70 mg/dL (Ez-PAVE): Lower is Better
LDL <55 vs <70 mg/dL (Ez-PAVE): Lower is Better
• LDL <55 mg/dL → ↓ events 33% (3 years)
• ↓ MI + ↓ revascularization
More intensive LDL lowering = better outcomes
Source
• TCTMD — ACC 2026 Conference Coverage
• NEJM (simultaneous publication)
Link (direct):
https://www.tctmd.com/news/
Practice Implication
• Target: LDL <55 mg/dL in ASCVD
• Strategy:
• Statin → + Ezetimibe → ± PCSK9
• Start early, treat aggressively