{"id":10110,"date":"2026-06-02T14:25:08","date_gmt":"2026-06-02T11:25:08","guid":{"rendered":"https:\/\/jordan-cardiac.org\/?p=10110"},"modified":"2026-06-02T14:25:08","modified_gmt":"2026-06-02T11:25:08","slug":"can-tirofiban-improve-90-day-outcomes-after-poor-response-to-stroke-thrombolysis","status":"publish","type":"post","link":"https:\/\/jordan-cardiac.org\/en\/can-tirofiban-improve-90-day-outcomes-after-poor-response-to-stroke-thrombolysis\/","title":{"rendered":"Can Tirofiban Improve 90-Day Outcomes After Poor Response to Stroke Thrombolysis?"},"content":{"rendered":"<div class=\"adM\"><br clear=\"all\" \/><br clear=\"all\" \/><\/div>\n<div>\n<div class=\"gmail_signature\" dir=\"ltr\" data-smartmail=\"gmail_signature\">\n<div>Can Tirofiban Improve 90-Day Outcomes After Poor Response to Stroke Thrombolysis?<\/div>\n<div>\nNew INSTANT trial suggests improved 90-day outcomes in selected ischemic stroke patients who:<br \/>\n* received Tenecteplase<br \/>\n* showed poor neurological improvement within 4\u201324 hours<br \/>\n* had no large- or medium-vessel occlusion, as these patients may be eligible for Mechanical Thrombectomy instead.<br \/>\n* Excellent recovery rates:<br \/>\n* 63.8% vs 52.2% with placebo.<br \/>\n* Symptomatic intracranial hemorrhage remained rare.<br \/>\n* Published in JAMA (May 8, 2026).<\/div>\n<div>\n<a href=\"http:\/\/jamanetwork.com\/journals\/jama\/fullarticle\/2848809\" target=\"_blank\" data-saferedirecturl=\"https:\/\/www.google.com\/url?q=http:\/\/jamanetwork.com\/journals\/jama\/fullarticle\/2848809&amp;source=gmail&amp;ust=1780485882058000&amp;usg=AOvVaw1fjMGtZNGIEJT8fo0E0bfX\" rel=\"noopener\">http:\/\/jamanetwork.com\/<wbr \/>journals\/jama\/fullarticle\/<wbr \/>2848809<\/a><\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Can Tirofiban Improve 90-Day Outcomes After Poor Response to Stroke Thrombolysis? New INSTANT trial suggests improved 90-day outcomes in selected ischemic stroke patients who: * received Tenecteplase * showed poor neurological improvement within 4\u201324 hours * had no large- or medium-vessel occlusion, as these patients may be eligible for Mechanical Thrombectomy instead. * Excellent recovery [&hellip;]<\/p>\n","protected":false},"author":145,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-10110","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"_links":{"self":[{"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/posts\/10110","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/users\/145"}],"replies":[{"embeddable":true,"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/comments?post=10110"}],"version-history":[{"count":1,"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/posts\/10110\/revisions"}],"predecessor-version":[{"id":10111,"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/posts\/10110\/revisions\/10111"}],"wp:attachment":[{"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/media?parent=10110"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/categories?post=10110"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/tags?post=10110"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}