{"id":5662,"date":"2025-02-17T09:48:30","date_gmt":"2025-02-17T06:48:30","guid":{"rendered":"https:\/\/jordan-cardiac.org\/?p=5662"},"modified":"2025-02-17T09:48:30","modified_gmt":"2025-02-17T06:48:30","slug":"avr-for-asymptomatic-severe-as-13-feb-2025-jama-cardiology","status":"publish","type":"post","link":"https:\/\/jordan-cardiac.org\/en\/avr-for-asymptomatic-severe-as-13-feb-2025-jama-cardiology\/","title":{"rendered":"AVR for Asymptomatic Severe AS 13 Feb 2025. JAMA Cardiology"},"content":{"rendered":"
AVR for Asymptomatic Severe AS<\/div>\n
13 Feb 2025. JAMA Cardiology .<\/div>\n
<\/div>\n
Key Takeaways from the Article: Cardiologists Recommend AVR for Asymptomatic Severe AS<\/div>\n
<\/span>1. <\/span>Default Treatment Recommendation:<\/div>\n
<\/span>\u2022 <\/span>Experts propose that aortic valve replacement (AVR) should be the standard treatment for asymptomatic severe aortic stenosis (AS) instead of clinical surveillance (CS).<\/div>\n
<\/span>\u2022 <\/span>Exceptions may apply due to anatomical or clinical factors.<\/div>\n
<\/span>2. <\/span>TAVR vs. SAVR \u2013 Case-by-Case Decision:<\/div>\n
<\/span>\u2022 <\/span>Both transcatheter AVR (TAVR) and surgical AVR (SAVR) can provide positive outcomes.<\/div>\n
<\/span>\u2022 <\/span>The choice should be based on anatomical suitability, patient age, comorbidities, and personal preference.<\/div>\n
<\/span>3. <\/span>Supporting Clinical Evidence:<\/div>\n
<\/span>\u2022 <\/span>EARLY TAVR Trial:<\/div>\n
<\/span>\u2022 <\/span>Included 901 patients (mean age: 75.8 years).<\/div>\n
<\/span>\u2022 <\/span>TAVR significantly reduced the primary endpoint (death, stroke, or hospitalization) compared to CS (26.8% vs. 45.3%).<\/div>\n
<\/span>\u2022 <\/span>AVATAR Trial:<\/div>\n
<\/span>\u2022 <\/span>Included 157 low-risk patients (mean age: 67 years).<\/div>\n
<\/span>\u2022 <\/span>Early SAVR led to better outcomes compared to conservative treatment (23.1% vs. 46.8% for primary endpoint).<\/div>\n
<\/span>4. <\/span>Concerns About Valve Durability:<\/div>\n
<\/span>\u2022 <\/span>While long-term durability of valves remains uncertain, early intervention is still recommended.<\/div>\n
<\/span>\u2022 <\/span>The timing of a second procedure is likely similar, regardless of early AVR or CS strategy.<\/div>\n
<\/span>5. <\/span>Addressing Public Health Concerns:<\/div>\n
<\/span>\u2022 <\/span>Delayed or inadequate treatment of severe AS remains a major issue.<\/div>\n
<\/span>\u2022 <\/span>Shifting to prompt AVR can improve patient outcomes and healthcare resource utilization.<\/div>\n
<\/span>6. <\/span>Call to Action:<\/div>\n
<\/span>\u2022 <\/span>Experts strongly advocate for a paradigm shift toward earlier AVR intervention.<\/div>\n
<\/span>\u2022 <\/span>\u201cIt is time to act.\u201d<\/div>\n
<\/div>\n
https:\/\/jamanetwork.com\/journals\/jamacardiology\/fullarticle\/2829881<\/a><\/div>\n","protected":false},"excerpt":{"rendered":"

AVR for Asymptomatic Severe AS 13 Feb 2025. JAMA Cardiology . Key Takeaways from the Article: Cardiologists Recommend AVR for Asymptomatic Severe AS 1. Default Treatment Recommendation: \u2022 Experts propose that aortic valve replacement (AVR) should be the standard treatment for asymptomatic severe aortic stenosis (AS) instead of clinical surveillance (CS). \u2022 Exceptions may apply […]<\/p>\n","protected":false},"author":1,"featured_media":5663,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-5662","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-uncategorized"],"_links":{"self":[{"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/posts\/5662","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/comments?post=5662"}],"version-history":[{"count":1,"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/posts\/5662\/revisions"}],"predecessor-version":[{"id":5665,"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/posts\/5662\/revisions\/5665"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/media\/5663"}],"wp:attachment":[{"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/media?parent=5662"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/categories?post=5662"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/tags?post=5662"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}