{"id":5998,"date":"2025-03-16T15:54:37","date_gmt":"2025-03-16T12:54:37","guid":{"rendered":"https:\/\/jordan-cardiac.org\/?p=5998"},"modified":"2025-03-16T15:54:59","modified_gmt":"2025-03-16T12:54:59","slug":"early-tavr-or-savr-for-asymptomatic-severe-as-limits-strokes-hospitalizations","status":"publish","type":"post","link":"https:\/\/jordan-cardiac.org\/en\/early-tavr-or-savr-for-asymptomatic-severe-as-limits-strokes-hospitalizations\/","title":{"rendered":"Early TAVR or SAVR for asymptomatic severe AS limits strokes, hospitalizations."},"content":{"rendered":"<div>Early TAVR or SAVR for asymptomatic severe AS limits strokes, hospitalizations.<\/div>\n<div><\/div>\n<div>The study titled \u201cEarly Aortic Valve Replacement in Asymptomatic Severe Aortic Stenosis: A Meta-Analysis of Randomized Controlled Trials\u201d by Sameena K. Brar et al. was published in the American Journal of Cardiology on March 7, 2025.<\/div>\n<div><\/div>\n<div>Key Findings:<\/div>\n<div><span class=\"Apple-tab-span\"> <\/span>\u2022<span class=\"Apple-tab-span\"> <\/span>Unplanned Hospitalizations: Early AVR significantly reduced the risk of unplanned hospitalizations (HR 0.42, 95% CI 0.33\u20130.53, p &lt; 0.001, I\u00b2\u202f=\u202f0%).<\/div>\n<div><span class=\"Apple-tab-span\"> <\/span>\u2022<span class=\"Apple-tab-span\"> <\/span>All-Cause Mortality: There was a trend towards reduced all-cause mortality with early AVR, though it did not reach statistical significance (HR 0.76, 95% CI 0.48\u20131.21, I\u00b2\u202f=\u202f42%).<\/div>\n<div><span class=\"Apple-tab-span\"> <\/span>\u2022<span class=\"Apple-tab-span\"> <\/span>Stroke Incidence: Stroke rates also trended lower with early AVR (HR 0.63, 95% CI 0.40\u20131.00, p\u202f=\u202f0.05, I\u00b2\u202f=\u202f0%).<\/div>\n<div><\/div>\n<div>These findings suggest that early AVR may offer clinical benefits by reducing adverse events, particularly unplanned rehospitalizations, in patients with asymptomatic severe AS. The authors propose that early AVR could be advantageous and recommend considering these results in future guideline updates.<\/div>\n<div><\/div>\n<div><a href=\"https:\/\/doi.org\/10.1016\/j.amjcard.2025.02.025\" target=\"_blank\" rel=\"noopener\">https:\/\/doi.org\/10.1016\/j.amjcard.2025.02.025<\/a><\/div>\n","protected":false},"excerpt":{"rendered":"<p>Early TAVR or SAVR for asymptomatic severe AS limits strokes, hospitalizations. The study titled \u201cEarly Aortic Valve Replacement in Asymptomatic Severe Aortic Stenosis: A Meta-Analysis of Randomized Controlled Trials\u201d by Sameena K. Brar et al. was published in the American Journal of Cardiology on March 7, 2025. Key Findings: \u2022 Unplanned Hospitalizations: Early AVR significantly [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-5998","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"_links":{"self":[{"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/posts\/5998","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/comments?post=5998"}],"version-history":[{"count":2,"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/posts\/5998\/revisions"}],"predecessor-version":[{"id":6000,"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/posts\/5998\/revisions\/6000"}],"wp:attachment":[{"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/media?parent=5998"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/categories?post=5998"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/tags?post=5998"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}