{"id":6341,"date":"2025-04-08T18:07:14","date_gmt":"2025-04-08T15:07:14","guid":{"rendered":"https:\/\/jordan-cardiac.org\/?p=6341"},"modified":"2025-04-08T18:07:14","modified_gmt":"2025-04-08T15:07:14","slug":"does-intensive-systolic-blood-pressure-sbp-control-reduce-cardiovascular-mortality-in-u-s-adults-aged-80","status":"publish","type":"post","link":"https:\/\/jordan-cardiac.org\/en\/does-intensive-systolic-blood-pressure-sbp-control-reduce-cardiovascular-mortality-in-u-s-adults-aged-80\/","title":{"rendered":"Does Intensive Systolic Blood Pressure (SBP) Control Reduce Cardiovascular Mortality in U.S. Adults Aged 80+?"},"content":{"rendered":"<div>Does Intensive Systolic Blood Pressure (SBP) Control Reduce Cardiovascular Mortality in U.S. Adults Aged 80+?<\/div>\n<div>Source: Yang H, Huang C, Sawano M, et al. JACC, Published online March 17, 2025<\/div>\n<div>DOI: 10.1016\/j.jacc.2025.01.033<\/div>\n<div><\/div>\n<div>1. Background<\/div>\n<div><span> \u2022 Current BP guidelines support intensive SBP control but lack specific evidence for individuals aged 80 years and older.<\/span><\/div>\n<div><span> \u2022 This study evaluated the association between SBP levels and cardiovascular mortality in U.S. adults aged 80+ on antihypertensive therapy.<\/span><\/div>\n<div><\/div>\n<div>2. Methods<\/div>\n<div><span> \u2022 Data from 1,593 adults aged 80+ (1988\u20132014) from NHANES, linked to the National Death Index (follow-up through 2019).<\/span><\/div>\n<div><span> \u2022 SBP categorized into 3 groups:<\/span><\/div>\n<div><span> \u2022 &lt;130 mmHg<\/span><\/div>\n<div><span> \u2022 130\u2013160 mmHg (reference group, based on ACC\/AHA and ESC guidelines)<\/span><\/div>\n<div><span> \u2022 &gt;160 mmHg<\/span><\/div>\n<div><span> \u2022 SBP was measured according to standard protocols; the mean of the 2nd and 3rd readings was used.<\/span><\/div>\n<div><span> \u2022 Primary outcome: Cardiovascular disease (CVD) mortality.<\/span><\/div>\n<div><span> \u2022 Mean follow-up: 6.7 year.<\/span><\/div>\n<div><\/div>\n<div>3. Key Findings<\/div>\n<div><span> \u2022 Total 1,295 deaths during follow-up; 596 (46%) were from cardiovascular causes.<\/span><\/div>\n<div><span> \u2022 Lower SBP (&lt;130 mmHg) was associated with a reduced risk of cardiovascular death:<\/span><\/div>\n<div><span> \u2022 Adjusted Hazard Ratio (HR) for SBP &lt;130 mmHg vs. 130\u2013160 mmHg: 0.74<\/span><\/div>\n<div><span> \u2022 Higher SBP (&gt;145 mmHg) was associated with increased cardiovascular mortality risk.<\/span><\/div>\n<div><span> \u2022 Findings were consistent despite the population being aged 80+, a group often underrepresented in trials.<\/span><\/div>\n<div><\/div>\n<div>4. Conclusions<\/div>\n<div><span> \u2022 Intensive SBP control (&lt;130 mmHg) is associated with lower cardiovascular mortality in U.S. adults aged 80+ on antihypertensive treatment.<\/span><\/div>\n<div><span> \u2022 These results support current guidelines promoting lower SBP targets, even in older populations.<\/span><\/div>\n<div><a href=\"https:\/\/www.acc.org\/Latest-in-Cardiology\/Journal-Scans\/2025\/03\/24\/13\/52\/Does-Intensive-SBP-Control-Reduce-CVD-Mortality-acc-2025\">https:\/\/www.acc.org\/Latest-in-Cardiology\/Journal-Scans\/2025\/03\/24\/13\/52\/Does-Intensive-SBP-Control-Reduce-CVD-Mortality-acc-2025<\/a><\/div>\n","protected":false},"excerpt":{"rendered":"<p>Does Intensive Systolic Blood Pressure (SBP) Control Reduce Cardiovascular Mortality in U.S. Adults Aged 80+? Source: Yang H, Huang C, Sawano M, et al. JACC, Published online March 17, 2025 DOI: 10.1016\/j.jacc.2025.01.033 1. Background \u2022 Current BP guidelines support intensive SBP control but lack specific evidence for individuals aged 80 years and older. \u2022 This [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-6341","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"_links":{"self":[{"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/posts\/6341","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/comments?post=6341"}],"version-history":[{"count":1,"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/posts\/6341\/revisions"}],"predecessor-version":[{"id":6343,"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/posts\/6341\/revisions\/6343"}],"wp:attachment":[{"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/media?parent=6341"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/categories?post=6341"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/tags?post=6341"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}