{"id":6587,"date":"2025-04-23T12:43:54","date_gmt":"2025-04-23T09:43:54","guid":{"rendered":"https:\/\/jordan-cardiac.org\/?p=6587"},"modified":"2025-04-23T12:43:54","modified_gmt":"2025-04-23T09:43:54","slug":"transcatheter-mitral-valve-replacement-system","status":"publish","type":"post","link":"https:\/\/jordan-cardiac.org\/en\/transcatheter-mitral-valve-replacement-system\/","title":{"rendered":"Transcatheter Mitral Valve Replacement System"},"content":{"rendered":"<div>Transcatheter Mitral Valve Replacement System<\/div>\n<div><\/div>\n<div>Source: Radiology Business<\/div>\n<div>Date of Publication: April 15, 2025<\/div>\n<div><\/div>\n<div>Take-Home Messages:<\/div>\n<div><span> 1. CE Mark Approval:<\/span><\/div>\n<div><span> \u2022 Edwards Lifesciences received CE mark approval for the Sapien M3 transcatheter mitral valve replacement (TMVR) system.<\/span><\/div>\n<div><span> \u2022 Targeted for patients with symptomatic mitral regurgitation (MR) who are not suitable for surgery or TEER (transcatheter edge-to-edge repair).<\/span><\/div>\n<div><span> 2. Device &amp; Procedure:<\/span><\/div>\n<div><span> \u2022 The Sapien M3 system is delivered via transfemoral venous access using a steerable sheath.<\/span><\/div>\n<div><span> \u2022 The procedure involves two steps:<\/span><\/div>\n<div><span> \u2022 A dock is deployed that wraps around the native mitral leaflets.<\/span><\/div>\n<div><span> \u2022 The Sapien M3 valve is then implanted within the dock, creating a secure landing zone.<\/span><\/div>\n<div><span> 3. Platform &amp; Experience:<\/span><\/div>\n<div><span> \u2022 The device is based on Edwards\u2019 Sapien platform, which has been used in 8,000+ mitral procedures.<\/span><\/div>\n<div><span> \u2022 Edwards is now the only company offering both replacement and repair options for mitral and tricuspid valves.<\/span><\/div>\n<div><span> 4. Clinical Importance:<\/span><\/div>\n<div><span> \u2022 Mitral regurgitation is the most common valvular heart disease and often leads to debilitating symptoms.<\/span><\/div>\n<div><span> \u2022 The Sapien M3 offers a new treatment pathway for patients unsuitable for existing therapies.<\/span><\/div>\n<div><span> 5. Future Outlook:<\/span><\/div>\n<div><span> \u2022 Results from the ENCIRCLE pivotal trial (evaluating safety and effectiveness) expected in late 2025.<\/span><\/div>\n<div><span> \u2022 The system is not yet approved by the U.S. FDA.<\/span><\/div>\n<div><a href=\"https:\/\/www.edwards.com\/healthcare-professionals\/trial\/encircle-hcp?utm_source=chatgpt.com\">https:\/\/www.edwards.com\/healthcare-professionals\/trial\/encircle-hcp?utm_source=chatgpt.com<\/a><\/div>\n","protected":false},"excerpt":{"rendered":"<p>Transcatheter Mitral Valve Replacement System Source: Radiology Business Date of Publication: April 15, 2025 Take-Home Messages: 1. CE Mark Approval: \u2022 Edwards Lifesciences received CE mark approval for the Sapien M3 transcatheter mitral valve replacement (TMVR) system. \u2022 Targeted for patients with symptomatic mitral regurgitation (MR) who are not suitable for surgery or TEER (transcatheter [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-6587","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"_links":{"self":[{"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/posts\/6587","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/comments?post=6587"}],"version-history":[{"count":1,"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/posts\/6587\/revisions"}],"predecessor-version":[{"id":6588,"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/posts\/6587\/revisions\/6588"}],"wp:attachment":[{"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/media?parent=6587"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/categories?post=6587"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/tags?post=6587"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}