{"id":8004,"date":"2025-07-21T00:15:58","date_gmt":"2025-07-20T21:15:58","guid":{"rendered":"https:\/\/jordan-cardiac.org\/?p=8004"},"modified":"2025-07-21T00:15:58","modified_gmt":"2025-07-20T21:15:58","slug":"relationship-between-exercise-induced-cardiac-troponin-elevations-and-occult-coronary-atherosclerosis-in-middle-aged-athletes","status":"publish","type":"post","link":"https:\/\/jordan-cardiac.org\/en\/relationship-between-exercise-induced-cardiac-troponin-elevations-and-occult-coronary-atherosclerosis-in-middle-aged-athletes\/","title":{"rendered":"Relationship Between Exercise-Induced Cardiac Troponin Elevations and Occult Coronary Atherosclerosis in Middle-Aged Athletes"},"content":{"rendered":"

Relationship Between Exercise-Induced Cardiac Troponin Elevations and Occult Coronary Atherosclerosis in Middle-Aged Athletes<\/span><\/p>\n

Published by Medscape on July 18, 2025.<\/span>
\nJournal:<\/span>
\nJournal of the American College of Cardiology (JACC)<\/span><\/p>\n

Key Findings:<\/span>
\n1. Background:<\/span>
\nCardiac troponin (cTn), a marker of heart muscle injury, often rises after intense physical exercise. However, the clinical meaning of these postexercise elevations, especially their link to hidden (occult) coronary artery disease, is unclear.<\/span>
\n2. Study Design:<\/span>
\n\u2022 Included 1,011 middle-aged recreational athletes (median age 56) participating in long-distance sports.<\/span>
\n\u2022 Measured high-sensitivity troponin T and I (hs-cTnT, hs-cTnI) before and after exercise.<\/span>
\n\u2022 Selected 68 high responders and 34 low responders for cardiac CT scans to assess coronary atherosclerosis using CAD-RADS and CT-FFR.<\/span>
\n3. Results:<\/span>
\n\u2022 No significant difference in the prevalence or severity of coronary atherosclerosis between high vs low troponin responders:<\/span>
\n\u2022 CAD-RADS > 0 in 67.6% of high vs 50.0% of low responders.<\/span>
\n\u2022 Median coronary calcium scores and CT-FFR outcomes were statistically similar.<\/span>
\n\u2022 Weak correlations were found between postexercise troponin levels and CAD-RADS classifications (R\u00b2 = 4\u20138%).<\/span>
\n4. Conclusion:<\/span>
\nPostexercise elevations in cardiac troponin are not strongly linked to the presence or severity of occult coronary atherosclerosis in recreational middle-aged athletes.<\/span>
\nThis suggests that most of the variation in exercise-induced troponin response is physiological, not pathological.<\/span><\/p>\n

Clinical Implication:<\/span><\/p>\n

High cardiac troponin levels after exercise, even if above clinical thresholds, do not necessarily indicate hidden coronary artery disease in healthy athletes and should be interpreted with caution.<\/span><\/p>\n

\"\ud83d\udd17\"\u00a0Link:\u00a0<\/span>https:\/\/www.jacc.org\/doi\/10.1016\/j.jacc.2025.04.017<\/a><\/p>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

Relationship Between Exercise-Induced Cardiac Troponin Elevations and Occult Coronary Atherosclerosis in Middle-Aged Athletes Published by Medscape on July 18, 2025. Journal: Journal of the American College of Cardiology (JACC) Key Findings: 1. Background: Cardiac troponin (cTn), a marker of heart muscle injury, often rises after intense physical exercise. However, the clinical meaning of these postexercise […]<\/p>\n","protected":false},"author":145,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-8004","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"_links":{"self":[{"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/posts\/8004","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/users\/145"}],"replies":[{"embeddable":true,"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/comments?post=8004"}],"version-history":[{"count":1,"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/posts\/8004\/revisions"}],"predecessor-version":[{"id":8005,"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/posts\/8004\/revisions\/8005"}],"wp:attachment":[{"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/media?parent=8004"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/categories?post=8004"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/tags?post=8004"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}