{"id":8148,"date":"2025-07-27T09:03:52","date_gmt":"2025-07-27T06:03:52","guid":{"rendered":"https:\/\/jordan-cardiac.org\/?p=8148"},"modified":"2025-07-27T09:03:52","modified_gmt":"2025-07-27T06:03:52","slug":"beating-atrial-fibrillation-sinus-rhythm-wins-ablation-plus-lifestyle-change-is-the-new-gold-standard-for-af","status":"publish","type":"post","link":"https:\/\/jordan-cardiac.org\/en\/beating-atrial-fibrillation-sinus-rhythm-wins-ablation-plus-lifestyle-change-is-the-new-gold-standard-for-af\/","title":{"rendered":"Beating Atrial Fibrillation Sinus Rhythm Wins Ablation Plus Lifestyle Change Is the New Gold Standard for AF."},"content":{"rendered":"<div>Beating Atrial Fibrillation<\/div>\n<div>Sinus Rhythm Wins<\/div>\n<div>Ablation Plus Lifestyle Change Is the New Gold Standard for AF.<\/div>\n<div><\/div>\n<div>Published: July 24, 2025 \u2013 Medscape<\/div>\n<div><\/div>\n<div>Key Notes:<\/div>\n<div><\/div>\n<div>1. PRAGUE-25 Trial \u2013 Main Finding<\/div>\n<div><span> \u2022 Compared catheter ablation (CA) vs. lifestyle modification + antiarrhythmic drugs in AF patients.<\/span><\/div>\n<div><span> \u2022 At 12 months: 73% in CA group free of AF vs. 34.6% in the lifestyle+drug group.<\/span><\/div>\n<div><span> \u2022 At 24 months: 55.6% (CA) vs. 24.7% (non-invasive group).<\/span><\/div>\n<div><span> \u2022 Conclusion: CA is more effective at maintaining sinus rhythm (SR).<\/span><\/div>\n<div>\u00a02. Experts Recommend a Combined Strategy<\/div>\n<div><span> \u2022 Best outcomes come from ablation + risk factor control.<\/span><\/div>\n<div><span> \u2022 Lifestyle change improves ablation durability.<\/span><\/div>\n<div>3. Why Sinus Rhythm (SR) Matters<\/div>\n<div><span> \u2022 SR linked to lower risk of:<\/span><\/div>\n<div><span> \u2022 Stroke, death, bleeding, and cardiac arrest (CABANA trial).<\/span><\/div>\n<div><span> \u2022 All-cause death reduced by 41% in patients maintaining SR.<\/span><\/div>\n<div>4. Guidelines Have Shifted<\/div>\n<div><span> \u2022 Recent updates (2023 AHA\/ACC\/HRS): Early rhythm control is now preferred.<\/span><\/div>\n<div><span> \u2022 Rhythm control is especially important in younger patients and those with heart failure.<\/span><\/div>\n<div>5. Treatment Should Be Personalized<\/div>\n<div><span> \u2022 Not every patient needs ablation, but all should be informed.<\/span><\/div>\n<div><span> \u2022 Antiarrhythmic drugs may help post-ablation, but relapse is common long-term.<\/span><\/div>\n<div><span> \u2022 Lifestyle change is difficult but essential. GLP-1 agonists may support weight loss in AF patients.<\/span><\/div>\n<div><\/div>\n<div>Anticoagulation after AF Ablation<\/div>\n<div><\/div>\n<div>Even after successful ablation, most patients still need anticoagulants if their CHA\u2082DS\u2082-VASc score is high, because AF can silently return and stroke risk remains.<\/div>\n<div>(ESC 2020 &amp; EHRA 2023 Guidelines)<\/div>\n<div><\/div>\n<div><\/div>\n<div><a href=\"http:\/\/www.medscape.com\/viewarticle\/sinus-rhythm-afib-ablation-trial\">http:\/\/www.medscape.com\/viewarticle\/sinus-rhythm-afib-ablation-trial<\/a><\/div>\n","protected":false},"excerpt":{"rendered":"<p>Beating Atrial Fibrillation Sinus Rhythm Wins Ablation Plus Lifestyle Change Is the New Gold Standard for AF. Published: July 24, 2025 \u2013 Medscape Key Notes: 1. PRAGUE-25 Trial \u2013 Main Finding \u2022 Compared catheter ablation (CA) vs. lifestyle modification + antiarrhythmic drugs in AF patients. \u2022 At 12 months: 73% in CA group free of [&hellip;]<\/p>\n","protected":false},"author":145,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-8148","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"_links":{"self":[{"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/posts\/8148","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/users\/145"}],"replies":[{"embeddable":true,"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/comments?post=8148"}],"version-history":[{"count":1,"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/posts\/8148\/revisions"}],"predecessor-version":[{"id":8149,"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/posts\/8148\/revisions\/8149"}],"wp:attachment":[{"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/media?parent=8148"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/categories?post=8148"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/tags?post=8148"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}