{"id":8197,"date":"2025-08-02T18:26:30","date_gmt":"2025-08-02T15:26:30","guid":{"rendered":"https:\/\/jordan-cardiac.org\/?p=8197"},"modified":"2025-08-02T18:26:30","modified_gmt":"2025-08-02T15:26:30","slug":"restarting-doac-too-early-after-a-serious-bleed-may-be-risky","status":"publish","type":"post","link":"https:\/\/jordan-cardiac.org\/en\/restarting-doac-too-early-after-a-serious-bleed-may-be-risky\/","title":{"rendered":"Restarting DOAC Too Early After a Serious Bleed May Be Risky"},"content":{"rendered":"<div>Restarting DOAC Too Early After a Serious Bleed May Be Risky<\/div>\n<div><\/div>\n<div>Medscape Medical News, July 31, 2025<\/div>\n<div><\/div>\n<div>Key Points:<\/div>\n<div><span> 1. Background:<\/span><\/div>\n<div>\u2003\u2022 Doctors often struggle with when to restart blood thinners (DOACs) after a serious bleeding event in atrial fibrillation (AF) patients.<\/div>\n<div><span> 2. The Study:<\/span><\/div>\n<div>\u2003\u2022 More than 10,000 patients in Denmark with serious bleeding events (intracranial, GI, or nasal) while on DOACs were analyzed.<\/div>\n<div>\u2003\u2022 Two groups were compared:<\/div>\n<div>\u2003\u2003\u2013 Early restart: Resumed DOACs within 60 days<\/div>\n<div>\u2003\u2003\u2013 Late restart: Resumed DOACs after 60 days<\/div>\n<div><span> 3. Key Results:<\/span><\/div>\n<div>\u2003\u2022 \u201cThere is little to gain by restarting DOACs too soon after a serious bleeding event.\u201d \u2014 Dr. Nour Al-Hussainy (Study Lead)<\/div>\n<div>\u00a0 \u00a0 \u00a0 4. Guideline Summary \u2013 When to Restart Anticoagulation (AF patients):<\/div>\n<div>\u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0ESC 2020 and AHA\/ACC\/HRS 2023 recommend resuming oral anticoagulation based on bleeding type and individualized stroke vs. bleeding risk:<\/div>\n<div>\u2003\u2022 GI bleeding: Restart after 7\u201314 days, once bleeding is controlled.<\/div>\n<div>\u2003\u2022 Intracranial hemorrhage (ICH): Delay 4\u20138 weeks, depending on neurological recovery and risk factors.<\/div>\n<div>\u2003\u2192 Supported as Class IIa recommendation (moderate strength of evidence) in both guidelines.<\/div>\n<div><\/div>\n<div><a href=\"https:\/\/click.mail.medscape.com\/?qs=2a59868a37b5aee87fe31555c5def2916f251b73c51009f880c8a7d4de72712fada547e1646682dd0d28cfc2c7dc6db8022625603cf1de6585994af58a4ed781\">https:\/\/click.mail.medscape.com\/?qs=2a59868a37b5aee87fe31555c5def2916f251b73c51009f880c8a7d4de72712fada547e1646682dd0d28cfc2c7dc6db8022625603cf1de6585994af58a4ed781<\/a><\/div>\n<div><\/div>\n<div><a href=\"https:\/\/professional.heart.org\/-\/media\/PHD-Files-2\/Science-News\/Clinical-Update-Slides\/AHA-Clinical-Update-2023-Guideline-Diagnosis-Management-AFib-Slide-Set.pdf\">https:\/\/professional.heart.org\/-\/media\/PHD-Files-2\/Science-News\/Clinical-Update-Slides\/AHA-Clinical-Update-2023-Guideline-Diagnosis-Management-AFib-Slide-Set.pdf<\/a><\/div>\n<div><\/div>\n<div><a href=\"https:\/\/academic.oup.com\/eurheartj\/article\/42\/5\/373\/5899003\">https:\/\/academic.oup.com\/eurheartj\/article\/42\/5\/373\/5899003<\/a><\/div>\n<div><\/div>\n","protected":false},"excerpt":{"rendered":"<p>Restarting DOAC Too Early After a Serious Bleed May Be Risky Medscape Medical News, July 31, 2025 Key Points: 1. Background: \u2003\u2022 Doctors often struggle with when to restart blood thinners (DOACs) after a serious bleeding event in atrial fibrillation (AF) patients. 2. The Study: \u2003\u2022 More than 10,000 patients in Denmark with serious bleeding [&hellip;]<\/p>\n","protected":false},"author":145,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-8197","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"_links":{"self":[{"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/posts\/8197","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/users\/145"}],"replies":[{"embeddable":true,"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/comments?post=8197"}],"version-history":[{"count":1,"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/posts\/8197\/revisions"}],"predecessor-version":[{"id":8198,"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/posts\/8197\/revisions\/8198"}],"wp:attachment":[{"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/media?parent=8197"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/categories?post=8197"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/tags?post=8197"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}