{"id":8948,"date":"2025-10-21T09:16:28","date_gmt":"2025-10-21T06:16:28","guid":{"rendered":"https:\/\/jordan-cardiac.org\/?p=8948"},"modified":"2025-10-21T09:16:28","modified_gmt":"2025-10-21T06:16:28","slug":"insight-from-the-jcs-2025-conference-october-17-2","status":"publish","type":"post","link":"https:\/\/jordan-cardiac.org\/en\/insight-from-the-jcs-2025-conference-october-17-2\/","title":{"rendered":"Insight from the JCS 2025 Conference (October 17)"},"content":{"rendered":"
Insight from the JCS 2025 Conference (October 17)<\/div>\n
<\/div>\n
Dr. Tanya Alhaj Hassan -Cardiac Intensivist<\/div>\n
<\/div>\n
Topic: Renal Function Preservation After Cardiac Surgery<\/div>\n
Session: Post-operative Cardiac ICU Management (Oct 17 2025)<\/div>\n
<\/div>\n
1. Opening question<\/div>\n
\u2022 She began by asking:<\/span><\/div>\n
\u201cWhat do you think is the best early marker of renal injury after cardiac surgery?\u201d<\/div>\n
\u2022 Audience replies included:<\/span><\/div>\n
\u2192 KFT (Creatinine, BUN) and urine output,<\/div>\n
\u2192 She noted both are late indicators, reflecting kidney damage after it has already occurred.<\/div>\n
<\/div>\n
2. Classical vs modern concepts<\/div>\n
\u2022 Traditional monitoring relies on creatinine rise > 48 h or urine output < 0.5 mL\/kg\/h, which delays recognition.<\/span><\/div>\n
\u2022 2025 consensus emphasizes \u201cfunctional + structural\u201d injury markers.<\/span><\/div>\n
<\/div>\n
3. Emerging biomarkers (\u201cMolecular 1 and 2\u201d) \u2013 AKI panel<\/div>\n
1. Molecular 1: Neutrophil Gelatinase-Associated Lipocalin (NGAL)<\/span><\/div>\n
\u2022 Rises within 2\u20133 hours post-CPB.<\/span><\/div>\n
\u2022 Predicts AKI 48 h earlier than serum creatinine.<\/span><\/div>\n
2. Molecular 2: TIMP-2 \u00d7 IGFBP-7 (Index of cell-cycle arrest)<\/span><\/div>\n
\u2022 Detects tubular stress before irreversible injury.<\/span><\/div>\n
\u2022 Incorporated into the 2025 KDIGO-AKI early-warning algorithm.<\/span><\/div>\n
<\/div>\n
\u2022 Both now included in several peri-operative renal-risk scoring systems.<\/span><\/div>\n
<\/div>\n
4. Clinical application in cardiac surgery<\/div>\n
\u2022 High-risk groups: prolonged CPB, low cardiac output, ECMO, combined valve procedures.<\/span><\/div>\n
\u2022 Use point-of-care urine NGAL\/TIMP-2\u00b7IGFBP-7 assays for early identification.<\/span><\/div>\n
\u2022 When positive \u2192 start \u201crenal bundle\u201d within 3 hours:<\/span><\/div>\n
\u2022 optimize hemodynamics and perfusion pressure,<\/span><\/div>\n
\u2022 avoid nephrotoxins,<\/span><\/div>\n
\u2022 adjust diuretics & contrast use,<\/span><\/div>\n
\u2022 guided fluid management (e.g., balanced crystalloids + dynamic preload assessment).<\/span><\/div>\n
<\/div>\n
5. ICU integration and multidisciplinary care<\/div>\n
\u2022 Cardiac intensivist, nephrologist, perfusionist, and ICU nursing team should act jointly.<\/span><\/div>\n
\u2022 Biomarkers allow personalized renal protection rather than \u201cone-size-fits-all.\u201d<\/span><\/div>\n
\u2022 Combined use with hemodynamic AI dashboards gives real-time risk visualization.<\/span><\/div>\n
<\/div>\n
\u00a06. Key take-home messages<\/div>\n
\u2022 Creatinine \u2191 = too late \u2192 aim for molecular alerts within hours.<\/span><\/div>\n
\u2022 Early recognition = renal recovery.<\/span><\/div>\n
\u2022 2025 era focus: move from AKI diagnosis to AKI prevention.<\/span><\/div>\n
\u2022 Jordanian ICUs can pioneer regional adoption of molecular AKI panels within cardiac programs.<\/span><\/div>\n","protected":false},"excerpt":{"rendered":"

Insight from the JCS 2025 Conference (October 17) Dr. Tanya Alhaj Hassan -Cardiac Intensivist Topic: Renal Function Preservation After Cardiac Surgery Session: Post-operative Cardiac ICU Management (Oct 17 2025) 1. Opening question \u2022 She began by asking: \u201cWhat do you think is the best early marker of renal injury after cardiac surgery?\u201d \u2022 Audience replies […]<\/p>\n","protected":false},"author":145,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-8948","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"_links":{"self":[{"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/posts\/8948","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/users\/145"}],"replies":[{"embeddable":true,"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/comments?post=8948"}],"version-history":[{"count":1,"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/posts\/8948\/revisions"}],"predecessor-version":[{"id":8949,"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/posts\/8948\/revisions\/8949"}],"wp:attachment":[{"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/media?parent=8948"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/categories?post=8948"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/tags?post=8948"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}