{"id":9158,"date":"2025-11-10T16:56:54","date_gmt":"2025-11-10T13:56:54","guid":{"rendered":"https:\/\/jordan-cardiac.org\/?p=9158"},"modified":"2025-11-10T16:56:54","modified_gmt":"2025-11-10T13:56:54","slug":"mitral-annular-calcificationmac-and-heart-failure-risk-ajc-2025","status":"publish","type":"post","link":"https:\/\/jordan-cardiac.org\/en\/mitral-annular-calcificationmac-and-heart-failure-risk-ajc-2025\/","title":{"rendered":"Mitral Annular Calcification(MAC) and Heart Failure Risk (AJC, 2025)"},"content":{"rendered":"<div>Mitral Annular Calcification(MAC) and Heart Failure Risk (AJC, 2025)<\/div>\n<div><\/div>\n<div>Source: Pressman G, et al. The American Journal of Cardiology.<\/div>\n<div>Reported in medical news, Nov 5, 2025.<\/div>\n<div><\/div>\n<div>Keynotes:<\/div>\n<div>1-Study design:<\/div>\n<div>database analysis of &gt;21,000 patients (MAC vs. no-MAC), all aged &gt;50 and free of prior heart failure.<\/div>\n<div><\/div>\n<div>2-Key findings:<\/div>\n<div><span> \u2022 Patients with MAC were:<\/span><\/div>\n<div><span> \u2022 3.8\u00d7 more likely to develop HFpEF<\/span><\/div>\n<div><span> \u2022 2.2\u00d7 more likely to develop HFrEF<\/span><\/div>\n<div><span> \u2022 2.8\u00d7 more likely to develop any heart failure<\/span><\/div>\n<div><span> \u2022 HFpEF + MAC patients had higher rates of hospitalization, ICU admission, valve replacement, and pacemaker implantation.<\/span><\/div>\n<div><\/div>\n<div>3-Comorbidities:<\/div>\n<div>MAC was also linked to greater risks of ischemic heart disease, stroke, aortic stenosis, acute renal failure, and even cardiogenic shock.<\/div>\n<div><\/div>\n<div>Conclusion:<\/div>\n<div>Mitral annular calcification is a strong, independent predictor of heart failure\u2014especially HFpEF\u2014with risk far exceeding that of obesity across BMI categories.<\/div>\n<div><\/div>\n<div><a href=\"https:\/\/www.ajconline.org\/article\/S0002-9149(25)00660-5\/fulltext\">https:\/\/www.ajconline.org\/article\/S0002-9149(25)00660-5\/fulltext<\/a><\/div>\n<div><\/div>\n","protected":false},"excerpt":{"rendered":"<p>Mitral Annular Calcification(MAC) and Heart Failure Risk (AJC, 2025) Source: Pressman G, et al. The American Journal of Cardiology. Reported in medical news, Nov 5, 2025. Keynotes: 1-Study design: database analysis of &gt;21,000 patients (MAC vs. no-MAC), all aged &gt;50 and free of prior heart failure. 2-Key findings: \u2022 Patients with MAC were: \u2022 3.8\u00d7 [&hellip;]<\/p>\n","protected":false},"author":145,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-9158","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"_links":{"self":[{"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/posts\/9158","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/users\/145"}],"replies":[{"embeddable":true,"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/comments?post=9158"}],"version-history":[{"count":1,"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/posts\/9158\/revisions"}],"predecessor-version":[{"id":9159,"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/posts\/9158\/revisions\/9159"}],"wp:attachment":[{"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/media?parent=9158"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/categories?post=9158"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/tags?post=9158"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}