{"id":9446,"date":"2026-01-04T17:14:03","date_gmt":"2026-01-04T14:14:03","guid":{"rendered":"https:\/\/jordan-cardiac.org\/?p=9446"},"modified":"2026-01-04T17:29:32","modified_gmt":"2026-01-04T14:29:32","slug":"restarting-anticoagulation-after-brain-hemorrhage-in-af-2025","status":"publish","type":"post","link":"https:\/\/jordan-cardiac.org\/en\/restarting-anticoagulation-after-brain-hemorrhage-in-af-2025\/","title":{"rendered":"Restarting Anticoagulation After Brain Hemorrhage in AF (2025)"},"content":{"rendered":"<div>Restarting Anticoagulation After Brain Hemorrhage in AF (2025)<\/div>\n<div><\/div>\n<div>Source: Medscape News UK<\/div>\n<div>Date: December 31, 2025<\/div>\n<div>Journal: Therapeutic Advances in Neurological Disorders (Dec 21, 2025)<\/div>\n<div><\/div>\n<div>Clinical Question<\/div>\n<div><span> \u2022 Should oral anticoagulants be restarted in patients with atrial fibrillation (AF) after intracerebral hemorrhage (ICH)?<\/span><\/div>\n<div><\/div>\n<div>What the Study Found<\/div>\n<div><span> \u2022 Restarting anticoagulation:<\/span><\/div>\n<div><span> \u2022 \u2193 Ischemic stroke by 80%<\/span><\/div>\n<div>(NNT = 9)<\/div>\n<div><span> \u2022 \u2193 Ischemic MACE by 59%<\/span><\/div>\n<div><span> \u2022 But:<\/span><\/div>\n<div><span> \u2022 \u2191 Recurrent ICH ~3-fold<\/span><\/div>\n<div>(NNH = 19)<\/div>\n<div><span> \u2022 \u2191 Hemorrhagic MACE<\/span><\/div>\n<div><span> \u2022 No difference in:<\/span><\/div>\n<div><span> \u2022 All-cause mortality<\/span><\/div>\n<div><span> \u2022 Cardiovascular death<\/span><\/div>\n<div><\/div>\n<div>Bottom Line<\/div>\n<div><span> \u2022 Restarting anticoagulation prevents strokes<\/span><\/div>\n<div><span> \u2022 But increases risk of recurrent brain bleeding<\/span><\/div>\n<div><span> \u2022 Overall survival is unchanged<\/span><\/div>\n<div><\/div>\n<div>In Practice<\/div>\n<div><span> \u2022 Restarting OAC may provide net benefit in carefully selected patients<\/span><\/div>\n<div><span> \u2022 Decision must be individualized, considering:<\/span><\/div>\n<div><span> \u2022 ICH type (lobar vs non-lobar)<\/span><\/div>\n<div><span> \u2022 Baseline bleeding risk<\/span><\/div>\n<div><span> \u2022 Ischemic risk (CHA\u2082DS\u2082-VASc)<\/span><\/div>\n<div><span> \u2022 Comorbidities<\/span><\/div>\n<div><span> \u2022 Patient preferences<\/span><\/div>\n<div><\/div>\n<div>Key Message<\/div>\n<div><\/div>\n<div>After ICH, anticoagulation in AF is not \u201cyes or no\u201d \u2014 it is a personalized risk\u2013benefit decision.<\/div>\n<div><\/div>\n<div><a href=\"https:\/\/click.mail.medscape.com\/?qs=ed42f9088742cf9aae500c1509ea1ee3115b53f4fbe4831733be622c910f57c66cb4249873f11227d8f506ffbb87616cc6269f2366f97a199dfad9a8497c0d07\">https:\/\/click.mail.medscape.com\/?qs=ed42f9088742cf9aae500c1509ea1ee3115b53f4fbe4831733be622c910f57c66cb4249873f11227d8f506ffbb87616cc6269f2366f97a199dfad9a8497c0d07<\/a><\/div>\n<div><\/div>\n","protected":false},"excerpt":{"rendered":"<p>Restarting Anticoagulation After Brain Hemorrhage in AF (2025) Source: Medscape News UK Date: December 31, 2025 Journal: Therapeutic Advances in Neurological Disorders (Dec 21, 2025) Clinical Question \u2022 Should oral anticoagulants be restarted in patients with atrial fibrillation (AF) after intracerebral hemorrhage (ICH)? What the Study Found \u2022 Restarting anticoagulation: \u2022 \u2193 Ischemic stroke by [&hellip;]<\/p>\n","protected":false},"author":145,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-9446","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"_links":{"self":[{"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/posts\/9446","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/users\/145"}],"replies":[{"embeddable":true,"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/comments?post=9446"}],"version-history":[{"count":1,"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/posts\/9446\/revisions"}],"predecessor-version":[{"id":9447,"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/posts\/9446\/revisions\/9447"}],"wp:attachment":[{"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/media?parent=9446"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/categories?post=9446"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/tags?post=9446"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}