{"id":9895,"date":"2026-04-21T17:33:11","date_gmt":"2026-04-21T14:33:11","guid":{"rendered":"https:\/\/jordan-cardiac.org\/?p=9895"},"modified":"2026-04-21T17:33:11","modified_gmt":"2026-04-21T14:33:11","slug":"ivus-guided-pci-new-trial-insights-acc-2026","status":"publish","type":"post","link":"https:\/\/jordan-cardiac.org\/en\/ivus-guided-pci-new-trial-insights-acc-2026\/","title":{"rendered":"IVUS-Guided PCI \u2014 New Trial Insights (ACC 2026)"},"content":{"rendered":"<p>IVUS-Guided PCI \u2014 New Trial Insights (ACC 2026)<\/p>\n<p>\u2022\u2060 \u2060Two RCTs: OPTIMAL (left main) &amp; IVUS-CHIP (complex PCI)<br \/>\n\u2022\u2060 \u2060Compared:<br \/>\n* IVUS-guided vs angiography-guided PCI<\/p>\n<p>Key Results<br \/>\n\u2022\u2060 \u2060\u274c No superiority of IVUS on primary outcomes<br \/>\n\u2022\u2060 \u2060Trend toward:<br \/>\n* similar or slightly worse outcomes with IVUS (NS)<br \/>\n\u2022\u2060 \u2060\u2714\ufe0f Exception:<br \/>\n* \u2193 stent thrombosis with IVUS<\/p>\n<p>Interpretation<br \/>\n\u2022\u2060 \u2060Results unexpected vs prior studies\/meta-analyses<br \/>\n\u2022\u2060 \u2060Likely explanation:<br \/>\n\ud83d\udc49 Highly experienced operators in both arms<\/p>\n<p>Important Insight<br \/>\n\u2022\u2060 \u2060IVUS may:<br \/>\n* Improve operator skill over time<br \/>\n* Benefits become less visible in experts<\/p>\n<p>Practical Impact<br \/>\n\u2022\u2060 \u2060\u2757 Does NOT change current guidelines (still recommended)<br \/>\n\u2022\u2060 \u2060Suggests:<br \/>\n\ud83d\udc49 IVUS may be selective, not mandatory in all cases<\/p>\n<p>Limitations \/ Considerations<br \/>\n\u2022\u2060 \u2060\u2191 procedure time (~+34%)<br \/>\n\u2022\u2060 \u2060\u2191 cost<br \/>\n\u2022\u2060 \u2060Low incremental benefit in expert centers<\/p>\n<p>\ud83c\udfaf Take-home<br \/>\n\ud83d\udc49 IVUS remains valuable<br \/>\n\ud83d\udc49 But added benefit depends on operator experience<br \/>\n\ud83d\udc49 May be most useful in:<br \/>\n\u2022\u2060 \u2060Training<br \/>\n\u2022\u2060 \u2060Less experienced operators<br \/>\n\u2022\u2060 \u2060Selected complex cases<\/p>\n<p>Source: ACC 2026 + NEJM (OPTIMAL &amp; IVUS-CHIP)<\/p>\n<p><a href=\"https:\/\/www.medscape.com\/viewarticle\/unexpected-trial-results-raise-questions-about-benefits-ivus-2026a1000bxl\">https:\/\/www.medscape.com\/viewarticle\/unexpected-trial-results-raise-questions-about-benefits-ivus-2026a1000bxl<\/a><\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>IVUS-Guided PCI \u2014 New Trial Insights (ACC 2026) \u2022\u2060 \u2060Two RCTs: OPTIMAL (left main) &amp; IVUS-CHIP (complex PCI) \u2022\u2060 \u2060Compared: * IVUS-guided vs angiography-guided PCI Key Results \u2022\u2060 \u2060\u274c No superiority of IVUS on primary outcomes \u2022\u2060 \u2060Trend toward: * similar or slightly worse outcomes with IVUS (NS) \u2022\u2060 \u2060\u2714\ufe0f Exception: * \u2193 stent thrombosis [&hellip;]<\/p>\n","protected":false},"author":145,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-9895","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"_links":{"self":[{"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/posts\/9895","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/users\/145"}],"replies":[{"embeddable":true,"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/comments?post=9895"}],"version-history":[{"count":1,"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/posts\/9895\/revisions"}],"predecessor-version":[{"id":9896,"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/posts\/9895\/revisions\/9896"}],"wp:attachment":[{"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/media?parent=9895"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/categories?post=9895"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/jordan-cardiac.org\/en\/wp-json\/wp\/v2\/tags?post=9895"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}